Sheu-Ran Choi Selected Research

Hyperalgesia

1/2023	Phase-specific differential regulation of mechanical allodynia in a murine model of neuropathic pain by progesterone.
1/2022	Sigma-1 receptor increases intracellular calcium in cultured astrocytes and contributes to mechanical allodynia in a model of neuropathic pain.
12/2021	Intrathecal interleukin-1β decreases sigma-1 receptor expression in spinal astrocytes in a murine model of neuropathic pain.
1/2021	Inhibition of angiotensin converting enzyme induces mechanical allodynia through increasing substance P expression in mice.
11/2019	nNOS-PSD95 interactions activate the PKC-ε isoform leading to increased GluN1 phosphorylation and the development of neuropathic mechanical allodynia in mice.
10/2019	Inhibition of cytochrome P450c17 reduces spinal astrocyte activation in a mouse model of neuropathic pain via regulation of p38 MAPK phosphorylation.
8/2019	Spinal Nitric Oxide Synthase Type II Increases Neurosteroid-metabolizing Cytochrome P450c17 Expression in a Rodent Model of Neuropathic Pain.
1/2019	Spinal cytochrome P450c17 plays a key role in the development of neuropathic mechanical allodynia: Involvement of astrocyte sigma-1 receptors.
1/2019	Astrocyte D-serine modulates the activation of neuronal NOS leading to the development of mechanical allodynia in peripheral neuropathy.
1/2019	Inhibition of Cytochrome P450 Side-Chain Cleavage Attenuates the Development of Mechanical Allodynia by Reducing Spinal D-Serine Production in a Murine Model of Neuropathic Pain.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Sheu-Ran Choi Research Topics

Disease

24	Hyperalgesia 01/2023 - 03/2011
17	Pain (Aches) 11/2023 - 08/2011
15	Neuralgia (Stump Neuralgia) 01/2023 - 08/2013
6	Hypersensitivity (Allergy) 01/2022 - 08/2011
5	Peripheral Nerve Injuries 01/2022 - 01/2017
4	Peripheral Nervous System Diseases (PNS Diseases) 01/2023 - 01/2019
4	Inflammation (Inflammations) 09/2018 - 04/2014
2	Acute Pain 11/2023 - 01/2018
1	Chronic Pain 01/2023
1	Nervous System Trauma 01/2023
1	Burns 01/2021
1	Pleurisy (Pleuritis) 09/2018
1	Hypoxia (Hypoxemia) 01/2014
1	Thrombosis (Thrombus) 01/2014
1	Acidosis 03/2011
1	Ischemia 03/2011

Drug/Important Bio-Agent (IBA)

8	Sigma-1 ReceptorIBA 01/2022 - 08/2011
6	EnzymesIBA 01/2023 - 01/2019
6	2- (4- morpholino)ethyl- 1- phenylcyclohexane- 1- carboxylateIBA 01/2022 - 08/2011
6	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2021 - 08/2011
6	CarrageenanIBA 09/2018 - 04/2014
5	CytochromesIBA 01/2023 - 01/2019
5	N- (2- (3,4- Dichlorphenyl)ethyl)- N,N',N'- trimethyl- 1,2- ethandiaminIBA 01/2022 - 08/2013
5	N-Methylaspartate (NMDA)IBA 12/2021 - 10/2015
5	Serine (L-Serine)FDA Link 01/2019 - 10/2015
4	Ketoconazole (Nizoral)FDA LinkGeneric 01/2023 - 01/2019
3	Formaldehyde (Formol)FDA Link 11/2023 - 01/2018
3	Analgesics (Analgesic Drugs)IBA 11/2023 - 12/2021
3	Dehydroepiandrosterone (DHEA)IBA 01/2022 - 03/2016
3	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 11/2019 - 12/2016
3	p38 Mitogen-Activated Protein KinasesIBA 10/2019 - 09/2013
3	NeurosteroidsIBA 10/2019 - 03/2016
3	7-nitroindazoleIBA 01/2019 - 08/2011
3	Purinergic P2Y1 ReceptorsIBA 01/2017 - 01/2014
2	Progesterone FDA LinkGeneric 01/2023 - 01/2022
2	CalciumIBA 01/2022 - 08/2011
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 12/2021 - 01/2017
2	SB 203580IBA 10/2019 - 04/2014
2	Proteins (Proteins, Gene)FDA Link 08/2019 - 01/2014
2	serine racemaseIBA 01/2019 - 01/2017
2	fluorocitrateIBA 01/2019 - 12/2016
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2019 - 01/2017
2	Connexin 43 (Connexin43)IBA 01/2017 - 12/2016
2	2- iodo- N(6)- methyl- (N)- methanocarba- 2'- deoxyadenosine- 3',5'- bisphosphateIBA 01/2017 - 04/2014
2	NADPH Oxidase 2IBA 12/2016 - 08/2013
2	acetovanillone (apocynin)IBA 12/2016 - 08/2013
2	Adenosine Triphosphate (ATP)IBA 01/2014 - 03/2011
1	OrexinsIBA 11/2023
1	CorticosteroneIBA 11/2023
1	Hormones (Hormone)IBA 11/2023
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2023
1	Glial Fibrillary Acidic ProteinIBA 01/2023
1	Mifepristone (RU 486)FDA Link 01/2023
1	Finasteride (Propecia)FDA LinkGeneric 01/2023
1	Captopril (Capoten)FDA LinkGeneric 01/2021
1	Enalapril FDA LinkGeneric 01/2021
1	3- ((3,5- bis(trifluoromethyl)phenyl)methyloxy)- 2- phenylpiperidineIBA 01/2021
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2021
1	Substance PIBA 01/2021
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021
1	Protein Isoforms (Isoforms)IBA 11/2019
1	2- ((1H- benzo(d)(1,2,3)triazol- 5- ylamino)methyl)- 4,6- dichlorophenolIBA 11/2019
1	Messenger RNA (mRNA)IBA 08/2019
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 08/2019
1	Dizocilpine Maleate (Dizocilpine)IBA 01/2019
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2019
1	7-chlorokynurenic acidIBA 01/2019
1	LigandsIBA 01/2019
1	linsidomineIBA 01/2019
1	Aminoglutethimide (Cytadren)FDA Link 01/2019
1	Oxidoreductases (Dehydrogenase)IBA 01/2019
1	trilostane FDA Link 01/2019
1	Protein Kinase CIBA 01/2019
1	Bee Venoms (Bee Venom)IBA 09/2018
1	Aromatase (CYP19)IBA 01/2018
1	D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA 01/2017
1	PotassiumIBA 01/2017
1	InterleukinsIBA 01/2017
1	SaltsIBA 01/2017
1	serine O-sulfateIBA 01/2017
1	ConnexinsIBA 12/2016
1	CarbenoxoloneIBA 12/2016
1	IronIBA 12/2016
1	Peroxynitrous Acid (Peroxynitrite)IBA 12/2016
1	Peptides (Polypeptides)IBA 12/2016
1	Superoxides (Superoxide)IBA 12/2016
1	NADP (NADPH)IBA 12/2016
1	pregnenolone sulfateIBA 03/2016
1	2',3'-O-(2,4,6-trinitrophenyl)adenosine 5'-triphosphateIBA 03/2016
1	Mitogen-Activated Protein KinasesIBA 04/2014
1	Carbonic Anhydrase IIIBA 01/2014
1	AcidsIBA 01/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2013
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 08/2011

Therapy/Procedure

2	Therapeutics 01/2023 - 09/2018
1	Anesthesia 01/2021
1	Acupuncture Points (Acupuncture Point) 09/2018
1	Complementary Therapies (Alternative Medicine) 09/2018
1	Spinal Injections 12/2016
1	Injections 01/2014